RAA has been contributing since 2000 to clinical research projects on the study of anti-retroviral drugs.

PENTA (Pediatric European Network for the Treatment of AIDS) was established in 1991 and represents a collaboration between clinical HIV centers for the pediatric population in Europe. Clinical trials are mainly funded by the European Commission (through the EuroCoord project), governmental bodies in some European countries and with the support of the pharmaceutical industry.

The PENTA Clinical Trial Network, training activities and collaborative cohorts are under the umbrella of the PENTA Foundation for the treatment and care of children with HIV.

Many HIV-related questions find the answer in adult clinical trials and do not need to be repeated in clinical trials for children. However, the natural history of HIV with vertical transmission differs from adult HIV history and the tolerance to certain drugs administered to children may also be different.

PenPact 1 (PENTA 9 / PACTG 390) was the first PENTA study in our country after the Romanian Angel Appeal Foundation was designated to provide the management of PENTA studies in Romania.

EuroCoord (European Network of HIV / AIDS cohorts to coordinate HIV / AIDS) was established on February 6, 2006 to integrate projects between different partners and coordinate applications for funding through the EU Framework Program seven.

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